Today the President signed a bill that was primarily directed at port security issues but in it was a very clear attach on online gambling based around restricting the flow of cash into and out of the online casinos.
Many consider this underhanded as politically, voting against the bill would have then been used to show the respective lawmaker as 'weak on security' - stuffing it in with the ports made it hard for people to vote against it.
Online gambling is generally already considered illegal in the US based on bookmaking rules involving communications over telephone lines (Wire Act) but online poker has been able to move around these restrictions. No longer - this will have an impact of some sort, even if the poker companies seem to be planning to accept US customers in the future.
An excellent book on online gambling prohibitions is Dave Schwartz's 'Cutting The Wire'.
I personally see this as short sighted and totally the wrong way to go. Americans should have the freedom to play online poker, blackjack or whatever if they so desire.
Update: Dave Schwartz has written a comprehensive piece on the specifics of the bill:
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